Wexler Wallace is currently investigating claims on behalf of consumers of a class of diabetes drugs that have been linked to necrotizing genital infections called Fournier’s gangrene.
SGLT2 inhibitors like Invokana are used by millions of Americans with type 2 diabetes to lower blood sugar. However, the FDA has issued a warning to consumers that these drugs may be linked to a type of rare but life-threatening genital infection known as Fournier’s gangrene.
Fournier’s gangrene, also known as necrotizing fasciitis of the perineum, is a rare bacterial infection that attacks the genital region and perineum. This infection of the genitals and scrotum usually gets into the body via a cut or break in the skin and infects tissue that surrounds the muscles, nerves, fat, and blood vessels of the perineum. The infection spreads quickly and destroys the tissue.
On August 29, 2018, the FDA issued a health warning that multiple cases of Fournier’s gangrene were discovered in patients taking SGLT2 inhibitors, including Invokana, Farxiga, Invokamet, Jardiance, and others.
|Brand Name||Active Ingredient(s)|
|Invokamet||canagliflozin and metformin|
|Invokamet XR||canagliflozin and metformin extended-release|
|Xigduo XR||dapagliflozin and metformin extended-release|
|Qtern||dapagliflozin and saxagliptin|
|Glyxambi||empagliflozin and linagliptin|
|Synjardy||empagliflozin and metformin|
|Synjardy XR||empagliflozin and metformin extended-release|
|Segluromet||ertugliflozin and metformin|
|Steglujan||ertugliflozin and sitagliptin|
The FDA identified several cases over a five-year period from March 2013 to May 2018 where patients taking SGLT2 inhibitors as prescribed developed Fournier’s gangrene within several months of starting treatment. All of the reported cases required hospitalization and surgery to treat the condition, and one death has been reported.
Symptoms of Fournier’s Gangrene
Patients taking SGLT2 inhibitors should seek immediate medical attention if they experience symptoms of Fournier’s gangrene, such as:
- Tenderness, redness, or swelling of the genital or rectal area
- Fever exceeding 100.4 degrees Fahrenheit
- Unpleasant odor emanating from the affected skin tissue
- Crackling sound when touching the affected area
Report Your Fournier’s Gangrene Lawsuit
If you or a loved one have developed Fournier’s gangrene while taking an SGLT2 inhibitor, contact Wexler Wallace today by submitting the form below. Wexler Wallace also welcomes inquiries from other counsel considering referring a case with respect to Fournier’s gangrene injuries.